Searchable abstracts of presentations at key conferences in endocrinology

ea0014p505 | (1) | ECE2007

Growth hormone replacement therapy and metabolic parameters in adult-onset GH-deficiency: long-term effects.

Giavoli Claudia , Ferrante Emanuele , Bergamaschi Silvia , Cristina L Ronchi , Francesca Doanadio , Andrea Lania , Anna Spada , Paolo Beck-Peccoz

Aim of this study was to evaluate the impact of rhGH treatment on glucose and lipid metabolism in in 26 patients (17M and 9F, age 47.0±11.1 years) with adult onset GH deficiency. Metabolic parameters (fasting glucose and insulin, glycated haemoglobin, lipid profile, body composition, OGTT) and indices of insulin resistance (IR) and sensitivity (IS), i.e. homeostasis model assessment (HOMA-IR and derived ISI-HOMA), quantitative insulin check index (QUICKI), ISI-composite, ...